Article
The thyroglobulin gene as the first thyroid-specific susceptibility gene for autoimmune thyroid disease.
Trends in molecular medicine - 1 Jul 2004
Tomer Yaron, Greenberg David
Abstract excerpt
Recent linkage and association studies provide evidence for thyroglobulin (Tg) being an autoimmune thyroid disease (AITD) susceptibility gene. The Tg locus has been reported to be linked with AITD in two independent studies, and further analysis demonstrated that markers within the Tg gene were associated with AITD. Furthermore, missense single-nucleotide polymorphisms (SNPs) in the Tg gene were shown to be...
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