Article
Association of a thyroglobulin gene polymorphism with Hashimoto's thyroiditis in the Japanese population.
Clinical endocrinology - 1 Aug 2004
Ban Yoshiyuki, Tozaki Teruaki, Taniyama Matsuo, Tomita Motowo, Ban Yoshio
Abstract excerpt
OBJECTIVE: The aetiology of the autoimmune thyroid diseases (AITDs), Graves' disease (GD) and Hashimoto's thyroiditis is largely unknown. However, genetic susceptibility is believed to play a major role. Two whole genome scans from Japan and from the USA identified a locus on chromosome 8q24 which showed evidence for linkage with AITD and HT. Recent studies have demonstrated an association between a Tg...
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