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Article

RTK/ERK pathway under natural selection associated with prostate cancer.

PloS one - 1 Jan 2013

Chen Yang, Xin Xianxiang, Li Jie, Xu Jianfeng, Yu Xiaoxiang, Li Tianyu, Mo Zengnan, Hu Yanling

Abstract excerpt

Prostate cancer (PCa) is a global disease causing large numbers of deaths every year. Recent studies have indicated the RTK/ERK pathway might be a key pathway in the development of PCa. However, the exact association and evolution-based mechanism remain unclear. This study was conducted by combining genotypic and phenotypic data from the Chinese Consortium for Prostate Cancer Genetics (ChinaPCa) with related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24223781
DOI: 10.1371/journal.pone.0078254
PMCID: PMC3817240

Genes

EGFR
ERBB2
PTK2
RAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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