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Article

Germline BAP1 mutations induce a Warburg effect.

Cell death and differentiation - 1 Oct 2017

Bononi Angela, Yang Haining, Giorgi Carlotta, Patergnani Simone, Pellegrini Laura, Su Mingming, Xie Guoxiang, Signorato Valentina, Pastorino Sandra, Morris Paul, Sakamoto Greg, Kuchay Shafi, Gaudino Giovanni, Pass Harvey I, Napolitano Andrea, Pinton Paolo, Jia Wei, Carbone Michele

Abstract excerpt

Carriers of heterozygous germline BAP1 mutations (BAP1+/-) develop cancer. We studied plasma from 16 BAP1+/- individuals from 2 families carrying different germline BAP1 mutations and 30 BAP1 wild-type (BAP1WT) controls from these same families. Plasma samples were analyzed by liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS), ultra-performance liquid chromatography triple quadrupole mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28665402
DOI: 10.1038/cdd.2017.95
PMCID: PMC5596430

Genes

BAP1

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