Article
FOXE1 association with differentiated thyroid cancer and its progression.
Thyroid : official journal of the American Thyroid Association - 1 May 2014
Penna-Martinez Marissa, Epp Friederike, Kahles Heinrich, Ramos-Lopez Elizabeth, Hinsch Nora, Hansmann Martin-Leo, Selkinski Ivan, Grünwald Frank, Holzer Katharina, Bechstein Wolf O, Zeuzem Stefan, Vorländer Christian, Badenhoop Klaus
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) near thyroid transcription factor genes (FOXE1 rs965513/NKX2-1 rs944289) have been shown to be associated with differentiated thyroid cancer (DTC) in Caucasoid populations. We investigated the role of those SNPs in German patients with DTC and also extended our analysis to tumor stages and lymphocytic infiltration of the tumors (ITL). METHODS: Patients with DTC...
Read the complete abstract on PubMed