Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening of BMPR1a for pathogenic mutations in familial colorectal cancer type X families from Newfoundland.

Familial cancer - 1 Apr 2018

Evans Daniel R, Green Jane S, Woods Michael O

Abstract excerpt

The Canadian province of Newfoundland and Labrador (NL) reports one of the highest incidence rates of familial colorectal cancer (CRC) worldwide. The NL population is an invaluable resource for studying genetic disorders because of a unique ancestry, and a willingness to participate in research studies. Familial colorectal cancer type X (FCCTX) describes a cluster of families with strong predisposition for CRC,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein Receptors, Type I
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to DNA Mutational Analysis

Share to Early Detection of Cancer

Share to Genetic Testing

Share to Incidence

Share to Newfoundland and Labrador

Source

Identifiers

PMID: 28660566
DOI: 10.1007/s10689-017-0016-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening of BMPR1a for pathogenic mutations in familial colorectal cancer type X families from Newfoundland.PMID 28660566Read ↗

Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other population-based studies.Semantic proximity Read ↗

BMPR2 as a Novel Predisposition Gene for Hereditary Colorectal Polyposis.Semantic proximity Read ↗

Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.Semantic proximity Read ↗

Evaluation of a population-based approach to familial colorectal cancer.Semantic proximity Read ↗

Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of <i>BMPR1A</i> loss of functionSemantic proximity Read ↗

High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes.Semantic proximity Read ↗

Evaluation of germline BMP4 mutation as a cause of colorectal cancer.Semantic proximity Read ↗

BMPR1A and SMAD4 mutations in juvenile polyposis syndrome: clinicopathological and genetic data from two congolese patientsSemantic proximity Read ↗

Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X.Semantic proximity Read ↗

A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptorSemantic proximity Read ↗

Familial juvenile polyposis syndrome with a de novo germline missense variant in BMPR1A gene: a case reportSemantic proximity Read ↗

The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.