Article
Normal phototransduction in Drosophila photoreceptors lacking an InsP(3) receptor gene.
Molecular and cellular neurosciences - 1 May 2000
Raghu P, Colley N J, Webel R, James T, Hasan G, Danin M, Selinger Z, Hardie R C
Abstract excerpt
The Drosophila light-sensitive channels TRP and TRPL are prototypical members of an ion channel family responsible for a variety of receptor-mediated Ca(2+) influx phenomena, including store-operated calcium influx. While phospholipase Cbeta is essential, downstream events leading to TRP and TRPL activation remain unclear. We investigated the role of the InsP(3) receptor (InsP(3)R) by generating mosaic eyes...
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