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Article

West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5

29 Jun 2017

Abstract excerpt

ABSTRACT West Nile virus (WNV) is a mosquito-borne flavivirus that causes epidemics of encephalitis and viscerotropic disease worldwide. This virus has spread rapidly and has posed a significant public health threat since the outbreak in New York City in 1999. The interferon (IFN)-mediated antiviral response represents an important component of virus-host interactions and plays an essential role in regulating...

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PMID: 28659477
DOI: 10.1128/jvi.02396-16

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