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Article

A brief review of the genetics and pharmacogenetics of opioid use disorders.

Dialogues in clinical neuroscience - 1 Sept 2017

Berrettini Wade

Abstract excerpt

Increased physician prescribing of opioids to treat chronic nonprogressive pain has been accompanied by an increase in opioid addiction. Twin studies of opioid addiction are consistent with an inherited component of risk, approximately 50%. Several genome-wide association study (GWAS) reports indicate that genetic risk for opioid addiction is conveyed by many alleles of small effect (odds ratios <1.5). These...

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Share to Cytochrome P-450 CYP2B6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29302220
PMCID: PMC5741106

Genes

OPRM1
CNIH3
KCNC1
KCNG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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