Article
Experimental evolution reveals an effective avenue to release catabolite repression via mutations in XylR.
Proceedings of the National Academy of Sciences of the United States of America - 11 Jul 2017
Sievert Christian, Nieves Lizbeth M, Panyon Larry A, Loeffler Taylor, Morris Chandler, Cartwright Reed A, Wang Xuan
Abstract excerpt
Microbial production of fuels and chemicals from lignocellulosic biomass provides promising biorenewable alternatives to the conventional petroleum-based products. However, heterogeneous sugar composition of lignocellulosic biomass hinders efficient microbial conversion due to carbon catabolite repression. The most abundant sugar monomers in lignocellulosic biomass materials are glucose and xylose. Although...
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