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Exploring the complexity of xylitol production in the fungal cell factory Aspergillus niger.

Enzyme and microbial technology - 1 Feb 2025

Müller Astrid, Meng Jiali, Kuijpers Robin, Mäkelä Miia R, de Vries Ronald P

Abstract excerpt

Production of xylitol from agricultural by-products offers a promising approach for the circular bioeconomy. This study investigates the roles of transcription factors XlnR and CreA in xylitol production from wheat bran in Aspergillus niger by generating strains with a constitutively active XlnR (XlnRc, V756F mutation) and/or deletion of creA, in a previously generated xylitol-producing strain. The XlnRc mutation...

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PMID: 39591728
DOI: 10.1016/j.enzmictec.2024.110550

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