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Article

Transcriptome-wide piRNA profiling in human brains of Alzheimer's disease.

Neurobiology of aging - 1 Sept 2017

Qiu Wenying, Guo Xiaoyun, Lin Xiandong, Yang Qian, Zhang Wanying, Zhang Yong, Zuo Lingjun, Zhu Yong, Li Chiang-Shan R, Ma Chao, Luo Xingguang

Abstract excerpt

Discovered in the brains of multiple animal species, piRNAs may contribute to the pathogenesis of neuropsychiatric illnesses. The present study aimed to identify brain piRNAs across transcriptome that are associated with Alzheimer's disease (AD). Prefrontal cortical tissues of 6 AD cases and 6 controls were examined for piRNA expression levels using an Arraystar HG19 piRNA array (containing 23,677 piRNAs) and...

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Identifiers

PMID: 28654860
DOI: 10.1016/j.neurobiolaging.2017.05.020
PMCID: PMC5542056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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