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Identification of circRNAs linked to Alzheimer's disease and related dementias

16 Feb 2023

Abstract excerpt

INTRODUCTION: Circular RNAs (circRNAs) exhibit selective expression in the brain and differential regulation in Alzheimer's disease (AD). To explore the role of circRNAs in AD, we investigated how circRNA expression varies between brain regions and with AD-related stress in human neuronal precursor cells (NPCs). METHODS: Ribosomal RNA-depleted hippocampus RNA-sequencing data were generated. Differentially...

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PMID: 36795937
DOI: 10.1002/alz.12960

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