Article
Association between genetic polymorphism of the angiotensin-converting enzyme and diabetic nephropathy: a meta-analysis comprising 26,580 subjects.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2012
Wang Furu, Fang Qiaoqiao, Yu Ningle, Zhao Deyu, Zhang Yimei, Wang Jin, Wang Quan, Zhou Xianfeng, Cao Xingjiang, Fan Xiangyong
Abstract excerpt
INTRODUCTION: The effect of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism on risk of diabetic nephropathy (DN) is still conflicting. The present meta-analysis was performed to evaluate the overall risk of this polymorphism associated with DN in different groups. MATERIALS AND METHODS: A predefined search was performed on 14,108 DN cases and 12,472 controls from 63 published studies by...
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