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Article

Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium

1 Mar 2022

Abstract excerpt

Rhinovirus (RV) infection of the bronchial epithelium is implicated in the vast majority of severe asthma exacerbations. Interestingly, the susceptibility of bronchial epithelium to RV infection is increased in persons with asthma. Bronchial smooth muscle (BSM) remodeling is an important feature of severe asthma pathophysiology, and its reduction using bronchial thermoplasty has been associated with a significant...

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PMID: 35354045
DOI: 10.1016/j.celrep.2022.110571

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