Article
ANGPTL4 T266M variant is associated with reduced cancer invasiveness.
Biochimica et biophysica acta. Molecular cell research - 1 Oct 2017
Tan Zhen Wei, Teo Ziqiang, Tan Carol, Choo Chee Chong, Loo Wei Sheng, Song Yiyang, Tam Zhi Yang, Ng Sean Pin, Koh Hong Zheng, Ng Yi Siang, Shochat Susana Geifman, Yau Yin Hoe, Zhu Pengcheng, Tan Nguan Soon
Abstract excerpt
Angiopoietin-like 4 (ANGPTL4) is a secretory protein that can be cleaved to form an N-terminal and a C-terminal protein. Studies performed thus far have linked ANGPTL4 to several cancer-related and metabolic processes. Notably, several point mutations in the C-terminal ANGPTL4 (cANGPTL4) have been reported, although no studies have been performed that ascribed these mutations to cancer-related and metabolic...
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