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Oxidative stress and inflammation regulation of sirtuins: New insights into common oral diseases

19 Aug 2022

Abstract excerpt

-dependent histone deacetylases, comprising seven members SIRT1-SIRT7. Sirtuins have been extensively studied in regulating ageing and age-related diseases. Sirtuins are also pivotal modulators in oxidative stress and inflammation, as they can regulate the expression and activation of downstream transcriptional factors (such as Forkhead box protein O3 (FOXO3a), nuclear factor erythroid 2-related factor 2 (Nrf2)...

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PMID: 36060706
DOI: 10.3389/fphys.2022.953078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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