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Article

Emery-Dreifuss muscular dystrophy-linked genes and centronuclear myopathy-linked genes regulate myonuclear movement by distinct mechanisms.

Molecular biology of the cell - 15 Aug 2017

Collins Mary Ann, Mandigo Torrey R, Camuglia Jaclyn M, Vazquez Gabriella A, Anderson Alyssa J, Hudson Christine H, Hanron John L, Folker Eric S

Abstract excerpt

Muscle cells are a syncytium in which the many nuclei are positioned to maximize the distance between adjacent nuclei. Although mispositioned nuclei are correlated with many muscle disorders, it is not known whether this common phenotype is the result of a common mechanism. To answer this question, we disrupted the expression of genes linked to Emery-Dreifuss muscular dystrophy (EDMD) and centronuclear myopathy...

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Source

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Identifiers

PMID: 28637766
DOI: 10.1091/mbc.E16-10-0721
PMCID: PMC5555658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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