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Article

Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling.

Biophysical journal - 20 Jun 2017

Zheng Wenjun, Wen Han, Iacobucci Gary J, Popescu Gabriela K

Abstract excerpt

N-Methyl-D-aspartate (NMDA) receptors are glutamate-gated excitatory channels that play essential roles in brain functions. High-resolution structures have been solved for an allosterically inhibited and agonist-bound form of a functional NMDA receptor; however, other key functional states (particularly the active open-channel state) were only resolved at moderate resolutions by cryo-electron microscopy...

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Identifiers

PMID: 28636915
DOI: 10.1016/j.bpj.2017.04.043
PMCID: PMC5479051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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