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Article

The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.

BMC bioinformatics - 11 Jan 2016

Pagan Moraima, Kloos Richard T, Lin Chu-Fang, Travers Kevin J, Matsuzaki Hajime, Tom Ed Y, Kim Su Yeon, Wong Mei G, Stewart Andrew C, Huang Jing, Walsh P Sean, Monroe Robert J, Kennedy Giulia C

Abstract excerpt

BACKGROUND: Thyroid carcinomas are known to harbor oncogenic driver mutations and advances in sequencing technology now allow the detection of these in fine needle aspiration biopsies (FNA). Recent work by The Cancer Genome Atlas (TCGA) Research Network has expanded the number of genetic alterations detected in papillary thyroid carcinomas (PTC). We sought to investigate the prevalence of these and other genetic...

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Source

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Identifiers

PMID: 26818556
DOI: 10.1186/s12859-015-0849-9
PMCID: PMC4895782

Genes

BRAF
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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