Article
Targeted Mutational Profiling and a Powerful Risk Score as Additional Tools for the Diagnosis of Papillary Thyroid Cancer.
Pathology oncology research : POR - 1 Jan 2020
Kocsis-Deák Barbara, Árvai Kristóf, Balla Bernadett, Tóbiás Bálint, Kohánka Andrea, Járay Balázs, Horányi János, Podani János, Takács István, Putz Zsuzsanna, Kósa János, Lakatos Péter
Abstract excerpt
Nowadays, the complementary diagnostics based on the suspicious thyroid lesion specific mutational state analysis is indispensable in the clinical practice. We aimed to test and validate our novel 568-mutational hotspot panel (23 cancer-related genes) on papillary thyroid cancers (PTCs) and their tumor-free pairs to find the most powerful mutation pattern related to PTC. The sequencing method was carried on with...
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