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Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration.

Ophthalmic genetics - 1 Jan 2000

García Montserrat, Álvarez Lydia, Fernández Ángela, González-Iglesias Héctor, Escribano Julio, Fernández-Vega Beatriz, Villota Eva, Fernández-Vega Cueto Luis, Fernández-Vega Álvaro, Coca-Prados Miguel

Abstract excerpt

BACKGROUND: To elucidate the potential role of single nucleotide polymorphisms (SNPs) in the metallothionein (MT) genes in Northern Spanish patients with age-related macular degeneration (AMD). METHODS: A total of 130 unrelated Northern Spanish natives diagnosed with AMD (46 dry, 35 neovascular, and 49 mixed) and 96 healthy controls, matched by age and ethnicity, were enrolled in a case-control study. DNA was...

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PMID: 28635422
DOI: 10.1080/13816810.2017.1288825

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