Article
Evidence for a higher resolution of HLA genotyping by a new NGS-based approach.
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 Sept 2017
Alizadeh M, Walencik A, Frassati C, Moskovtchenko P, Lafarge X, Verite F, Semana G
Abstract excerpt
With more than 16,000 alleles identified, the human leucocyte antigen (HLA) system is one of the most polymorphic regions of the human genome. Regarding the crucial role of HLA compatibility in transplantation and especially in Hematopoietic Stem Cell Transplantation, identification of HLA polymorphisms at a high-resolution level is of major interest. Recently, NGS technology has been proposed which appears to be...
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