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Article

New challenges, new opportunities: Next generation sequencing and its place in the advancement of HLA typing.

Human immunology - 1 Jul 2021

Bravo-Egana Valia, Sanders Holly, Chitnis Nilesh

Abstract excerpt

The Human Leukocyte Antigen (HLA) system has a critical role in immunorecognition, transplantation, and disease association. Early typing techniques provided the foundation for genotyping methods that revealed HLA as one of the most complex, polymorphic regions of the human genome. Next Generation Sequencing (NGS), the latest molecular technology introduced in clinical tissue typing laboratories, has demonstrated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33551127
DOI: 10.1016/j.humimm.2021.01.010

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