Characterisation of artefacts and drop-in events using STR-validator and single-cell analysis.

Abstract excerpt

There is a need to understand the occurrence of drop-in and their peak height distributions to further improve existing models to interpret complex DNA results. The necessary data is usually very time-consuming to collect. Here we present a practical approach for simultaneous characterisation of reproducible artefacts and drop-in contamination from negative controls. As an alternative to the traditional approach...

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