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Article

KCNQ1 gene polymorphism is associated with glycaemic response to treatment with DPP-4 inhibitors.

Diabetes research and clinical practice - 1 Aug 2017

Gotthardová Ivana, Javorský Martin, Klimčáková Lucia, Kvapil Milan, Schroner Zbynek, Kozárová Miriam, Malachovská Zuzana, Ürgeová Anna, Židzik Jozef, Tkáč Ivan

Abstract excerpt

AIMS: Only afew gene variants were associated with the response to dipeptidylpeptidase-4 inhibitors (DPP4I). KCNQ1 gene variants were previously related both to type 2 diabetes (T2D) and incretin effect. We hypothesized that T2D related KCNQ1 variants would be associated with smaller glucose-lowering effect of DDP4I. METHODS: We performed a retrospective study in 137 Caucasian subjects with T2D who were followed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28624668
DOI: 10.1016/j.diabres.2017.05.018

Genes

KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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