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Article

Moderate exercise training decreases inflammation in transgenic sickle cell mice.

Blood cells, molecules & diseases - 1 Mar 2018

Charrin Emmanuelle, Dubé John J, Connes Philippe, Pialoux Vincent, Ghosh Samit, Faes Camille, Ofori-Acquah Solomon F, Martin Cyril

Abstract excerpt

Chronic systemic inflammation is a pathophysiological feature of sickle cell disease (SCD). Considering that regular exercise exerts multiple beneficial health effects including anti-inflammatory actions, we investigated whether a treadmill training program could minimize the inflammatory state in transgenic sickle cell (SS) mice. To test this hypothesis, SS mice were subjected to a treadmill training protocol of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28624257
DOI: 10.1016/j.bcmd.2017.06.002

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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