Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BCOR Internal Tandem Duplication in High-grade Uterine Sarcomas.

The American journal of surgical pathology - 1 Mar 2018

Mariño-Enriquez Adrián, Lauria Alexandra, Przybyl Joanna, Ng Tony L, Kowalewska Magdalena, Debiec-Rychter Maria, Ganesan Raji, Sumathi Vaiyapuri, George Suzanne, McCluggage W Glenn, Nucci Marisa R, Lee Cheng-Han, Fletcher Jonathan A

Abstract excerpt

Endometrial stromal sarcomas (ESSs) are mesenchymal uterine tumors characterized by recurrent genetic events, most commonly chromosomal rearrangements, that create oncogenic gene fusions. High-grade endometrial stromal sarcomas (HG-ESSs), as defined in the 2014 World Health Organization Classification, typically contain oncogenic YWHAE-NUTM2 fusions; however, although not well characterized, there are tumors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neoplasm Grading
Share to Tandem Repeat Sequences

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alberta

Share to Biopsy

Share to Endometrial Neoplasms

Share to Europe

Share to Gene Duplication

Share to United States

Source

Identifiers

PMID: 29200103
DOI: 10.1097/PAS.0000000000000993

Genes

BCOR
YWHAE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BCOR Internal Tandem Duplication in High-grade Uterine Sarcomas.PMID 29200103Read ↗

A Pan-Cancer Landscape Analysis Reveals a Subset of Endometrial Stromal and Pediatric Tumors Defined by Internal Tandem Duplications of BCORSemantic proximity Read ↗

BCOR is a robust diagnostic immunohistochemical marker of genetically diverse high-grade endometrial stromal sarcoma, including tumors exhibiting variant morphology.Semantic proximity Read ↗

Endometrial Stromal Sarcomas With BCOR Internal Tandem Duplication and Variant BCOR/BCORL1 Rearrangements Resemble High-grade Endometrial Stromal Sarcomas With Recurrent CDK4 Pathway Alterations and MDM2 AmplificationsSemantic proximity Read ↗

Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplificationsSemantic proximity Read ↗

Endometrial stromal sarcoma – the new genetic paradigmSemantic proximity Read ↗

Novel EPC1 gene fusions in endometrial stromal sarcomaSemantic proximity Read ↗

Clinicopathological and genomic characterization of BCORL1-driven high-grade endometrial stromal sarcomas.Semantic proximity Read ↗

Metastatic high-grade endometrial stromal sarcoma (HG-ESS) with BCOR rearrangement: A case reportSemantic proximity Read ↗

Genomic and Transcriptomic Characterization Revealed the High Sensitivity of Targeted Therapy and Immunotherapy in a Subset of Endometrial Stromal SarcomaSemantic proximity Read ↗

Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of InfancySemantic proximity Read ↗

The biology of uterine sarcomas: A review and updateSemantic proximity Read ↗

Undifferentiated round cell sarcoma with BCOR internal tandem duplications (ITD) or YWHAE fusions: a clinicopathologic and molecular studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.