Article
Hedgehog signaling pathway as a new therapeutic target in pancreatic cancer.
World journal of gastroenterology - 7 Mar 2014
Onishi Hideya, Katano Mitsuo
Abstract excerpt
Pancreatic cancer is one of the most aggressive and difficult cancers to treat. Despite numerous research efforts, limited success has been achieved in the therapeutic management of patients with this disease. In the current review, we focus on one component of morphogenesis signaling, Hedgehog (Hh), with the aim of developing novel, effective therapies for the treatment of pancreatic cancer. Hh signaling...
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