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[Multiple sclerosis in the Republic of Bashkortostan: population-specific genetic predictors and the results of a 20-year clinical follow-up study].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2023

Timasheva Y R, Nasibullin T R, Tuktarova I A, Erdman V V, Galiullin T R, Lyutov O V, Bakhtiiarova K Z

Abstract excerpt

OBJECTIVE: Identification of a complex of genetic predictors of multiple sclerosis (MS) based on previously obtained results in genome-wide association studies of disease markers (GWAS markers) in a population of MS patients and healthy individuals of the Republic of Bashkortostan (Russian Federation) using polygenic detection. MATERIAL AND METHODS: The total study group consisted of 2048 people (641 patients...

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PMID: 37560832
DOI: 10.17116/jnevro202312307234

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