Article
[Genetic predisposition factors for multiple sclerosis (based on the data from genotyping patients of the Russian ethnic group)].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 1997
Gusev E I, Sudomoina M A, Boĭko A N, Turetskaia R L, Demina T L, Alekseev L P, Boldyreva M N, Trofimov D Iu, Undritsov I M, Favorova O O
Abstract excerpt
Patients' genotyping of Russian ethnic group with multiple sclerosis (MS) was performed for the first time in two loci of the main complex of histocompatibility: in DR HLA class II (gene DRB1) and in the locus of tumor necrosis factors (TNF). There was no difference in the incidence of alleles groups which correlated with some specificity of DR. Meanwhile TNF-a1 and TNF-a9 alleles were encountered significantly...
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