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Article

SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance

1 Nov 2018

Abstract excerpt

BACKGROUND: Sex-determining region Y-box (SRY-box) containing gene 9 (SOX9) expression confers cancer stem cell features. However, SOX9 function in intrahepatic cholangiocarcinoma (iCCA) is unknown. This study investigated the effects and underlying mechanisms of SOX9 in iCCA. METHODS: SOX9 expression in 59 iCCA patients was examined by immunohistochemistry. The association between SOX9 expression and clinical...

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PMID: 30420613
DOI: 10.1038/s41416-018-0338-9

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