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Article

Identification of PTPN22, ST6GAL1 and JAZF1 as psoriasis risk genes demonstrates shared pathogenesis between psoriasis and diabetes.

Experimental dermatology - 1 Nov 2017

Wang Honglei, Wang Zhenzhen, Rani Parimi Leela, Fu Xi'an, Yu Wenjun, Bao Fangfang, Yu Gongqi, Li Jianke, Li Lulu, Sun Lele, Yue Zhenhua, Zhao Qing, Pan Qing, Cao Jing, Wang Chuan, Chi Xiaojun, Wang Yaru, Yang Qing, Mi Zihao, Liu Hong, Zhang Furen

Abstract excerpt

The biological connections between psoriasis and diabetes have been suggested by epidemiological, immunological and genetic studies. To identify additional shared susceptibility loci and investigate shared pathogenesis between these two diseases, we genotyped 89 reported diabetes susceptibility loci in 4456 psoriasis cases and 6027 controls of Chinese population using the MassARRAY system from Sequenom. We...

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Share to Antigens, CD
Share to Co-Repressor Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus

Share to Genetic Loci

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Psoriasis

Share to Receptors, Antigen, T-Cell

Share to Sialyltransferases

Source

Identifiers

PMID: 28603863
DOI: 10.1111/exd.13393

Genes

JAZF1
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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