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Article

Overlapping Features of Psoriasis and Atopic Dermatitis: From Genetics to Immunopathogenesis to Phenotypes.

International journal of molecular sciences - 15 May 2022

Tsai Ya-Chu, Tsai Tsen-Fang

Abstract excerpt

Psoriasis (PSO) and atopic dermatitis (AD) were once considered to be mutually exclusive diseases, but gradually regarded as a spectrum of disease. Shared genetic loci of both diseases were noted in some populations, including Chinese. Shared immunopathogenesis involving Th17, Th1, Th22 cells, or even IL-13 was found in certain stages or phenotypes. This review discusses the overlapping genetic susceptibility,...

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Identifiers

PMID: 35628327
DOI: 10.3390/ijms23105518
PMCID: PMC9143118

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