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Genetic variability in the regulation of the expression cluster of MDR genes in patients with breast cancer.

Cancer chemotherapy and pharmacology - 1 Aug 2017

Tsyganov Matvey M, Freidin Maxim B, Ibragimova Marina K, Deryusheva Irina V, Kazantseva Polina V, Slonimskaya Elena M, Cherdyntseva Nadezhda V, Litviakov Nikolai V

Abstract excerpt

PURPOSE: We aimed to investigate the association between the polymorphism and expression patterns of multiple drug resistance genes (MDR) in breast cancer (BC). MATERIALS AND METHODS: The MDR gene expression levels were measured in tumor tissues of 106 breast cancer patients using quantitative real-time PCR. Affymetrix CytoScan™ HD Array chips were used to assess genotypes. Pairwise correlation analysis for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multidrug Resistance-Associated Protein 2

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Identifiers

PMID: 28601971
DOI: 10.1007/s00280-017-3354-1

Genes

ABCB1
ABCC1
ABCC2
ABCG2

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