Article
IFN-gamma priming of adipose-derived stromal cells at "physiological" hypoxia.
Journal of cellular physiology - 1 Feb 2018
Andreeva Elena R, Udartseva Olga O, Zhidkova Olga V, Buravkov Sergey V, Ezdakova Maria I, Buravkova Ludmila B
Abstract excerpt
Multipotent mesenchymal stromal cells (MSCs) are considered cue regulators of tissue remodeling. Their activity is strongly governed by local milieu, where O2 level is most important. The elevation of inflammatory mediators and acute O2 lowering may additionally modulate MSC activity. In present paper the priming effects of IFN-gamma on adipose tissue-derived MSCs (ASCs) at tissue-related O2 level (5%) and acute...
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