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Article

sFlt-1: A Double Regulator in Angiogenesis-related Diseases

3 Sept 2021

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor (VEGF) is a supergene family derived from a platelet growth factor. It plays a pivotal role in regulating angiogenesis and lymphangiogenesis. sFlt-1 is a soluble antagonist of VEGF with an essential effect of maintaining the balance of vascular growth. Recently, sFlt-1 has emerged as a new marker for early diagnosis and disease surveillance of angiogenesis-related...

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PMID: 34477512
DOI: 10.2174/1381612827666210902155015

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