Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ALCAR promote adult hippocampal neurogenesis by regulating cell-survival and cell death-related signals in rat model of Parkinson's disease like-phenotypes.

Neurochemistry international - 1 Sept 2017

Singh Sonu, Mishra Akanksha, Mishra Sandeep Kumar, Shukla Shubha

Abstract excerpt

Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons in the nigrostriatal pathway that leading to progressive motor and nonmotor symptoms. The formation of newborn neurons in the adult hippocampus is affected by many factors such as anxiety, depression and impairment in learning and memory that are commonly observed nonmotor symptoms in PD, indicating the role of adult...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hippocampus

Share to Neurogenesis

Share to Oxidopamine

Share to Parkinsonian Disorders

Share to Rats, Sprague-Dawley

Source

Identifiers

PMID: 28577987
DOI: 10.1016/j.neuint.2017.05.017

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ALCAR promote adult hippocampal neurogenesis by regulating cell-survival and cell death-related signals in rat model of Parkinson's disease like-phenotypes.PMID 28577987Read ↗

ALCAR Exerts Neuroprotective and Pro-Neurogenic Effects by Inhibition of Glial Activation and Oxidative Stress via Activation of the Wnt/β-Catenin Signaling in Parkinsonian Rats.Semantic proximity Read ↗

Death in the substantia nigra: a motor tragedySemantic proximity Read ↗

In vivo 6-OHDA-induced neurodegeneration and nigral autophagic markers expressionSemantic proximity Read ↗

Mitochondrial Dysfunction, Neurogenesis, and Epigenetics: Putative Implications for Amyotrophic Lateral Sclerosis Neurodegeneration and TreatmentSemantic proximity Read ↗

Uric Acid Enhances Neurogenesis in a Parkinsonian Model by Remodeling MitochondriaSemantic proximity Read ↗

Synergetic Therapeutic Efficacy of Fasudil and Bone Marrow Derived-Neuronal Stem Cell in a Parkinson's Disease Mouse ModelSemantic proximity Read ↗

Glycogen Synthase Kinase-3β Regulates Equilibrium Between Neurogenesis and Gliogenesis in Rat Model of Parkinson's Disease: a Crosstalk with Wnt and Notch Signaling.Semantic proximity Read ↗

Exploring cognitive and affective outcomes following bilateral 6-hydroxydopamine lesions of the substance nigra or striatum in ratsSemantic proximity Read ↗

Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling.Semantic proximity Read ↗

Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal deathSemantic proximity Read ↗

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.Semantic proximity Read ↗

Nigral injection of a proteasomal inhibitor, lactacystin, induces widespread glial cell activation and shows various phenotypes of Parkinson’s disease in young and adult mouseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.