Evidence for a novel exon in the coding region of the adenomatous polyposis coli (APC) gene.

doi:10.1006/geno.1995.1195

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Article

Evidence for a novel exon in the coding region of the adenomatous polyposis coli (APC) gene.

Genomics - 10 Aug 1995

Xia L, St Denis K A, Bapat B

Abstract excerpt

Germline mutations of the tumor suppressor gene APC cause familial adenomatous polyposis. Somatic APC alterations are involved in several sporadic neoplasms, including colorectal, duodenal, gastric, and esophageal carcinoma. The APC mRNA is encoded by 15 exons. Additional transcripts have been re...

Topics

Adenomatous Polyposis Coli
Amino Acid Sequence
Animals
Base Sequence
DNA Primers
DNA, Complementary
Exons
Humans
Introns
Mice
Molecular Sequence Data
Mutation
RNA, Messenger

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