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Article

Effect of multiple cycles of freeze-thawing on the RNA quality of lung cancer tissues.

Cell and tissue banking - 1 Sept 2017

Yu Keke, Xing Jie, Zhang Jie, Zhao Ruiying, Zhang Ye, Zhao Lanxiang

Abstract excerpt

RNA degradation is a major problem in tissue banking. We explored the effect of thawing flash-frozen biospecimens on the quality and integrity of RNA for genetic testing as well as for other cancer research studies. The histological quality of the frozen tumor sections was evaluated by using hematoxylin and eosin staining. RNA extraction from 60 lung cancer tissue samples subjected to various freeze/thaw cycles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28573389
DOI: 10.1007/s10561-016-9600-7

Genes

ALK
EML4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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