Article
Uncovering the pharmacological mechanisms of GuBenZhiKe decoction in treating chronic obstructive pulmonary disease by an integrative pharmacology strategy
2024-11-04
Abstract excerpt
<title>Abstract</title> <p>We aimed to study the mechanisms of GuBenZhiKe decoction (GBZKD) in treating Chronic obstructive pulmonary disease (COPD). Components of GBZKD were analyzed using liquid chromatography-mass spectrometry. ICR mice were exposed to cigarette smoke and administered lipopolysaccharide to establish a COPD model, followed by treatment with GBZKD. Lung function test, hematoxylin and eosin stain...
Topics
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- Cancer-related molecular mechanisms research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inflammasome and immune disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Metabolomics and Mass Spectrometry Studies
- Quinazolinone synthesis and applications
Identifiers and source
- Literature Corpus work
- e1fc780e-2651-5d9a-a601-ca549eab9625
- DOI
- 10.21203/rs.3.rs-5271698/v1
