Article
PAI-1 gene 4G/5G genotype: A risk factor for thrombosis in vessels of internal organs.
American journal of hematology - 1 Oct 2002
Balta Gunay, Altay Cigdem, Gurgey Aytemiz
Abstract excerpt
Although the common 4G/5G polymorphism in the promoter of the PAI-1 gene was suggested to be a risk factor for some of the thrombotic disorders, its significance in the development of thrombosis is still controversial. This study presents the data on a total of 357 patients with different types of thrombosis and 281 unrelated healthy controls. It was found that the 4G/4G genotype is associated with a higher risk...
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