Article
Prostaglandin E2 promotes human CD34+ cells homing through EP2 and EP4 in vitro.
Molecular medicine reports - 1 Jul 2017
Wang Yaqun, Lai Shuping, Tang Jing, Feng Chun, Liu Fangjie, Su Chang, Zou Waiyi, Chen Huizhen, Xu Duorong
Abstract excerpt
Recently, certain studies have demonstrated in vitro that prostaglandin E2 (PGE2) promotes human cluster of differentiation (CD)34+ cell homing. However, the sub‑type receptors activated by PGE2 are unknown, as the PGE2 receptor EP1-4 subtypes (EP1-4) are expressed on the membrane of human CD34+ cells. Based on the above, the present study aimed to screen the receptor subtype activity by PGE2 to promote human...
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