Article
[New biopsy at lung cancer progression: rational treatment of resistant lung cancer].
Nederlands tijdschrift voor geneeskunde - 1 Jan 2017
Hijmering-Kappelle L B M, van der Wekken A J, Hiltermann T J N, Groen H J M
Abstract excerpt
Nowadays, patients with advanced non-small cell lung cancer harbouring a driver mutation undergo targeted treatment. This results in profound tumour responses but inevitably induces resistance after approximately 9 to 12 months. In this article we consider the importance and clinical implications of taking new biopsies to retrieve information regarding resistance mechanisms. There is a shift in the use of other...
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