Article
From Biology to Therapy: Improvements of Therapeutic Options in Lung Cancer.
Anti-cancer agents in medicinal chemistry - 1 Jan 2018
Formisano Luigi, Jansen Valerie M, Marciano Roberta, Bianco Roberto
Abstract excerpt
Lung cancer is the leading cause of cancer-related mortality around the world, despite effective chemotherapeutic agents, the prognosis has remained poor for a long time. The discovery of molecular changes that drive lung cancer has led to a dramatic shift in the therapeutic landscape of this disease. In "in vitro" and "in vivo" models of NSCLC (Non-Small Cell Lung Cancer), angiogenesis blockade has demonstrated...
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