Article
Integration of Technical, Bioinformatic, and Variant Assessment Approaches in the Validation of a Targeted Next-Generation Sequencing Panel for Myeloid Malignancies.
Archives of pathology & laboratory medicine - 1 Jun 2017
Thomas Mariam, Sukhai Mahadeo A, Zhang Tong, Dolatshahi Roozbeh, Harbi Djamel, Garg Swati, Misyura Maksym, Pugh Trevor, Stockley Tracy L, Kamel-Reid Suzanne
Abstract excerpt
CONTEXT: - Detection of variants in hematologic malignancies is increasingly important because of a growing number of variants impacting diagnosis, prognosis, and treatment response, and as potential therapeutic targets. The use of next-generation sequencing technologies to detect variants in hematologic malignancies in a clinical diagnostic laboratory setting allows for efficient identification of routinely...
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