Article
Associating cellular epigenetic models with human phenotypes.
Nature reviews. Genetics - 1 Jul 2017
Lappalainen Tuuli, Greally John M
Abstract excerpt
Epigenetic association studies have been carried out to test the hypothesis that environmental perturbations trigger cellular reprogramming, with downstream effects on cellular function and phenotypes. There have now been numerous studies of the potential molecular mediators of epigenetic changes by epigenome-wide association studies (EWAS). However, a challenge for the field is the interpretation of the results...
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