Article
Genomic profile of human meningioma cell lines.
PloS one - 1 Jan 2017
Mei Yu, Bi Wenya Linda, Greenwald Noah F, Agar Nathalie Y, Beroukhim Rameen, Dunn Gavin P, Dunn Ian F
Abstract excerpt
Meningiomas, derived from arachnoid cap cells, are the most common intracranial tumor. High-grade meningiomas, as well as those located at the skull base or near venous sinuses, frequently recur and are challenging to manage. Next-generation sequencing is identifying novel pharmacologic targets in meningiomas to complement surgery and radiation. However, due to the lack of in vitro models, the importance and...
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