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Article

Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy.

Journal of neuromuscular diseases - 1 Jan 2000

Willmann Raffaella, Gordish-Dressman Heather, Meinen Sarina, Rüegg Markus A, Yu Qing, Nagaraju Kanneboyina, Kumar Ayar, Girgenrath Mahasweta, Coffey Caroline B M, Cruz Vivian, Van Ry Pam M, Bogdanik Laurent, Lutz Cathleen, Rutkowski Anne, Burkin Dean J

Abstract excerpt

Laminin-α2 related Congenital Muscular Dystrophy (LAMA2-CMD) is a progressive muscle disease caused by partial or complete deficiency of laminin-211, a skeletal muscle extracellular matrix protein. In the last decade, basic science research has queried underlying disease mechanisms in existing LAMA2-CMD murine models and identified possible clinical targets and pharmacological interventions. Experimental rigor in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28550268
DOI: 10.3233/JND-170217
PMCID: PMC5467719

Genes

LAMA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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