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Isolation of Phenotypically Distinct Cancer Cells Using Nanoparticle-Mediated Sorting

26 May 2017

Abstract excerpt

Isolating subpopulations of heterogeneous cancer cells is an important capability for the meaningful characterization of circulating tumor cells at different stages of tumor progression and during the epithelial-to-mesenchymal transition. Here, we present a microfluidic device that can separate phenotypically distinct subpopulations of cancer cells. Magnetic nanoparticles coated with antibodies against the...

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PMID: 28548481
DOI: 10.1021/acsami.7b05253

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